Tears of Guthix may refer to:
- Tears of Guthix (quest), the quest
- Tears of Guthix (Distraction and Diversion), the weekly Distraction and Diversion
- Tears of Guthix (music track), the music track
- The Tears of Guthix cavern, an area south of Lumbridge Swamp Caves
- Divine tears, gathered during Battle of Lumbridge
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