Each sip of Saradomin brew increases life points by 1000 and increases Defence by 1-4 levels (4% + 1). However, it also drains Strength, Attack, Magic, and Ranged levels by the same amount. Unlike any regular food, Saradomin brew does not drain the user's adrenaline.
This potion is one of very few ways to raise life points above the normal maximum. The boosting effect will not stack with rocktail, but it will stack with the warmth of a bonfire.
It is universally advised to only use this potion in combination with restore, super restore, or overload potions in order to counteract the draining of the player's Attack, Strength, Magic and Range stats. Without using restore potions the Saradomin brew will reduce a player's levels to under level 10 within 5-8 doses, depending on the player's stats. As this effectively defeats the point of using it by quickly rendering players nearly incapable of doing damage, it is generally avoided.
When it is ingested the chatbox message says, "You drink some of the foul liquid", unlike other potions message - "You drink some of your (potion's name). You have (1-3) doses left/You have finished your potion."
If you drink a Saradomin brew and enter the Wilderness, you will see in the chatbox "Your extreme potion bonus has been reduced.", and your defence bonus from the Saradomin brew will be reduced to the bonus of a super defence potion.
It is the only tradeable potion that cannot be modified with caviar.
Its price plummeted after the release of EoC, mainly due to the amount of times needed to click to heal a large amount of life points. Prior to EoC, a brew would heal a player with 99 Constitution about three times as much as a shark would. After EoC, however, a brew heals only 25% more life points than a shark and will only heal 500 life points per dose, while sharks can heal 1600 life points in one click. Their defence boost is also much weaker after the EoC.
With the release of Legacy Mode, Saradomin brews now heal 1000 LP per dose, twice what they healed post-EoC. This buff, combined with the players' LP system reverting to the 990/9900 system and the removal of Constitution level-based food healing, has once again made Saradomin brews one of the highest healing items in the game per inventory space. A 4 dose vial will heal 4000 LP total, while a flask can heal a maximum of 6000; by comparison, sharks and rocktails will heal 2000 and 2300 respectively.