Sam may refer to:

• Sam (barmaid), a barmaid at the Burthorpe Games Rooms
• Sam (certer), a certer in RuneScape Classic
• Sam (merchant), a team cape merchant in the Wilderness
• H.A.M. agent Sam
• Speedy Sam The Striker, a famous Gnome Baller
• Squire Sam, a Void Knight involved in Quiet Before the Swarm

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