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For running runes through the Abyss, see Abyss#Equipment for good gear suggestions.
|Effectiveness||Runecrafting level requirement||Details||Other requirements|
|*****||Level 1||Either through the skill or through rune running, you can make air runes. World 16 is the official world for running air runes. Air runes are best made with rune essence. If running airs, it can be easy to find a high level Runecrafter who can assist you in crafting multiple runes. If you find a player who can craft 6 or more air runes per essence, this can make you a profit of approximately 3,164 coins per trip. As you reach higher levels, you will be able to craft more runes per essence (if you craft them yourself), which further increases profit. See the Air Running Guide for more information on this topic. Bring everything that can to make you faster and efficient this is a every effective way being so close to Varrock, do not bring any armour besides anything to do with runecrafting or running/lightness. Drop off your pickaxe off at the bank on the way if you use it every Kg counts against you.||Rune Mysteries completed.|
|*****||Level 27||Crafting cosmic runes via Zanaris is a great money maker. There is also a bank close by. They sell for 233 each.||Abyss miniquest completed or Lost City completed|
|*****||Level 44||Crafting Nature runes via the abyss. Currently, more money can be made by making cosmic runes than nature runes.|
|*****||Level 44||Another method to crafting Nature Runes is by using your pure essence with Jiminua at Jiminua's Jungle Store North-West of the Nature Altar and she will un-note the desired amount of essence for 2 coins per essence (Don't sell it to her). Then run back to the Nature Altar and craft the essence and repeat this process.(335 profit per essence or around 8710 coins profit per trip). You need to have one space with noted pure essence and one space free for nature runes. It is recommended that you wear weight-reducing clothing to make this process more efficient. Be wary of monsters that can poison.|
|Level 44||One of the most popular methods of crafting nature runes is using a spirit graahk to teleport the player to the graahk hunter grounds that gives easy access to the nature altar. Although it requires level 57 summoning, the profits can quickly make up for the amount of time and money spent. The method is to summon the graahk, withdraw a full inventory of essence while wearing a nature tiara/ wicked hood (using runecrafting pouches if possible) and teleport to the hunting area. From there, run east along the northern wall of the village south and craft the essence into nature runes. Then, teleport back to a bank either using a ring of duelling or a ring of kinship. Using this method and assuming that one run can be completed every minute with small, medium, large and giant pouches in usage, one can earn about 80,000/hour.||Level 57 Summoning|
|*****||Level 50||At 50 Runecrafting you can enter the Runecrafting Guild and craft runes in The Great Orb Project, then sell the runes with no need to buy essence. This gives a modest profit since you get the full value of the runes in profit and you can make them a lot faster.|
|With your tokens from The Great Orb Project, you can purchase pure essence which currently sells for 15 coins or do the same things with water talisman which sell for 10,892 coins. See this page for a detailed calculator of value of items obtained from trading in tokens.|
|Level 54||Law runes are one of the best runes to craft for profit. They sell for roughly 419 coins in bulk on the Grand Exchange. This is a great cost-effective alternative.
Stocking up on normal logs and yew logs gives you an advantage if you have completed the Enlightened Journey quest. You can use the Balloon transport system from Castle wars to Entrana (One normal log required to travel to Entrana and one yew log required for the return trip). To reduce running time even more, you can stock up on rings of duelling to teleport straight to Castle Wars. Though it is up to you if you want to craft/enchant the rings yourself or buy them in bulk.
|Level 59||At level 59 Runecrafting you start to make two cosmic runes per essence. Two cosmic runes will sell for a 451 coin profit per pure essence, assuming you buy the essence.||Lost City completed|
|*****||Level 65||Craft death runes via the Abyss and Sell them via the Grand Exchange will nearly never be a problem. Deaths runes will sell for about 339 coins each, a profit of 324 coins each if you buy your essence.||Mourning's Ends Part II completed, Abyss miniquest completed|
|*****||Level 72||Craft Armadyl Runes. If both the Dust of Armadyl and the Pure Essence is bought, one can expect to make about 2.5k per essence. The only drawback is that it may be difficult to buy the Dust of Armadyl.
Note: Due to the Evolution of combat patch this is no longer an effective way of making money, since the price dropped in that patch making the runes worthless, the dust itself is worth more than the runes.
|Ritual of the Mahjarrat completed|
|*****||Level 77||Craft blood runes via the Abyss, which sell for about 479 coins each, a profit of 464 coins each if you buy your essence.||Legacy of Seergaze completed|
|*****||At this level, you can craft both blood and death runes, you can use all but one of the five runecrafting pouches, and depending on your Summoning level, you can summon an abyssal parasite or lurker. With these extras you can craft around 2,000 runes per hour by using the Abyss. You earn less per rune when compared to law runes or sticking to only blood runes or death runes, but the quantity you make will earn you more gold per hour in addition the little extra experience per rune if you only made law runes. With altar teleport tablets from the Great Orb Project, approximately 5,000 runes can be crafted per hour.||Legacy of Seergaze completed|
Mourning's Ends Part II completed
High Summoning level.
|*****||With the Drakan's Medallion from Branches of Darkmeyer, you have access to unlimited free teleports to both the Burgh de Rott bank and the Blood Altar. This is about as fast as going through the Abyss, but is a lot safer as you won't need to pass PKers and Abyssal monsters, and doesn't take a large investment in Amulets of glory.||Branches of Darkmeyer partially completed.|
|*****||Level 82||Running/Crafting double astral runes via Lunar Magic. Much like crafting double cosmic runes, there is some profit to be made here usually. Double astral crafting earns you about 505 coins per essence if you buy your essence.||Lunar Diplomacy completed|
|Level 91||Crafting double nature runes via the Abyss was widely considered to be one of the best money makers in the game, as making double runes more than doubles the net Runecrafting profits. If you have 57 summoning, you can summon the Spirit Graahk which enables you to do runs to the nature altar faster than the abyss, making it the preferable choice. Two nature runes per essence means a profit of 689 coins per essence, if you buy the essence. Using all 4 runecrafting pouches allows one to carry up to 54 essence at once and thus make 108 nature runes per trip, which is a total of 37,206 coins profit per trip. Under the right conditions, this method can make you a million gold in just about an hour. If you don't have 91 Runecrafting, you can go to world 36 (the nature running server) and there may be players offering free double natures (look for players usually dressed in gold).||Abyss miniquest completed Optional: 57 summoning|
|*****||Level 99||99 Runecrafting can be extremely difficult for non-member players (400 hours of game play to obtain), but at level 99, you make ten air runes per essence used. This can give you a profit of 205 coins per essence, or 5,740 coins per inventory. However, this method is NOT recommended for members as there are much more profitable ways to make money on pay-to-play.|