Killing corpse spiders
Requirements Corpse Spider

45 Magic recommended for Chain

Profit Experience gained
623,700 per hour

17,085 Multicombat experience
5,628 Constitution experience

Inputs Outputs

25 x Law rune (8,700)
25 x Earth rune (500)

600 x Spider silk (607,200)
13 x Staff (25,727)
5 x Staff of air (12,200)

Corpse spiders drop spider silk which is used in magic armour and weapons that give imbued components when dissassembled, keeping their price fairly steady. The method takes into account using Lumbridge Teleport to help with banking, crafting spider wands which require 2 spider silk or other items can also help with banking, this can be done with thread you bring or pick up as a drop. They also drop a staves of air or staves which should both be picked up, other drops include air runes, fire runes and earth runes which about covers the cost of the runes for teleportation.
Members have the option to use signs of the porter (IV are used for this calculation) which allow you to auto loot with space and it banks all the spider silk, this method almost completely eliminates banking (1-2 times per hour). Assuming you get 1200 spider silk in an hour you'll make a profit of 748,380