At level 20 Dungeoneering players (both F2P and P2P) may enter the Edgeville resource dungeon located in the east of the hill giant area where four limpwurt roots spawn making a reasonable amount of money from picking them up and selling them quickly on the Grand Exchange nearby. The banks in the Grand Exchange and in Edgeville are also nearby to deposit these picked up limpwurt roots. Alternatively, players with at least 32 Cooking that have completed the hard Varrock Tasks may use the Cooks' Guild bank which is considerably closer.
According to the official bestiary (now removed), hobgoblins often chew limpwurt roots, which may be a reference to the common drop of these roots for hobgoblins. In addition, the minitrice pet use them as food, which may be related to limpwurt roots being a common drop of cockatrices.
Three limpwurt roots are found in the chest in Evil Dave's compound in New Varrock. They can also be used to make strength potions, but the potions cost 5 zemomarks instead of coins.