|Release||25 April 2016 (Update)|
|Quest item||River of Blood|
|Destroy||You can reclaim it from Efaritay on the roof of Castle Drakan.|
|On death||Always kept outside Wild|
|Examine||A potion of wyrd blood, refined daeyalt and Ivandis's serum.|
The Extreme Guthix balance is an item used in River of Blood. It is made from Refined Daeyalt, Ivandis's Serum, and Wyrd blood that is obtained from Safalaan.
It is used to strengthen the River Salve so that it can cure the vampyrism of any who cross it. It is also used to help calm Safalaan's Wyrd bloodlust after the player subdues him.