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ESS or Ess may refer to:
- Rune essence, can only create free-to-play runes
- Pure essence, can create any type of rune
- The Elysian spirit shield, one of the spirit shields
- Esslings, creatures in the Runespan
- Esshounds, creatures in the Runespan
- Esswraiths, creatures in the Runespan
- Essjay, from the Diamond Jubilee