Claws of Guthix was a combat spell in the standard spellbook. Casting it required a Magic level of 60 in addition to having either a guthix staff or a void knight mace equipped. The spell was unlocked by completing the Mage Arena activity; it had to be cast 100 times within the arena itself in order to be used anywhere else. Upon a successful hit, Claws of Guthix had the chance of lowering the target's Defence by 5%.
However, neither Saradomin Strike nor Flames of Zamorak could be cast with a staff that boosts magic damage, while the Void Knight Mace increases magic damage by 10%, which could have increased Claws of Guthix's maximum hit to 330. With an arcane stream necklace as well, the total magic damage boost is 25%, which would have increased the max hit to 375.
Furthermore, if a player used a hexcrest or full slayer helmet while on a Slayer task with the aforementioned items, the total magic damage boost would have been 35%, increasing the max hit to 405. The highest hit known was 466, which was cast on another player in the Duel Arena using Charge, a guthix cape, the void knight mace, saradomin's hiss and boots, gloves, and ward of subjugation.
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- Previously, if the target's Defence level were reduced or boosted from the normal level, as would be the case after using a defence potion or something similar, the Defence level would remain unaffected by the spell. This was corrected on 10 January 2007.
- Before the update that allowed autocasting without a staff, Claws of Guthix was the only god spell that could be autocast, through the use of the void knight mace.
- Claws of Guthix was removed from RuneScape by the Evolution of Combat update on November 20, 2012.