Brother may refer to:
- Barrows brothers
- Brother Althric
- Brother Androe, at the Monastery
- Brother Bordiss, from Perils Of Ice Mountain quest
- Brother Brace, from Tutorial Island
- Brother Cedric, from Monk's Friend
- Brother Celerity, at the Monastery
- Brother Constantius, from Armies of Gielinor
- Brother Fintan, beacon keeper
- Brother Heinous, from 2012 Hallowe'en
- Brother Jered, at the Monastery
- Brother Kojo, from Clock Tower
- Brother Maledict, from The Slug Menace
- Brother Omad, at the Monastery
- Brother Righteous, from 2012 Hallowe'en
- Brother Tranquility, from The Great Brain Robbery
- Cook's brother
- Graahks brothers