A boss is a powerful, usually unique monster that is fought to accomplish an objective, be it the advancement or completion of a quest or minigame, or as part of a team player versus monster event. Many quests feature boss fights at their climaxes; such bosses are often the main antagonists of the quests or quest series, or are somehow related to the main antagonist(s). Some monsters that are commonly referred to as bosses are very powerful monsters that are commonly fought by teams of players in search of highly valuable drops. Many bosses have extremely high combat levels, and all of the strongest monsters in the game are bosses.
Dwarf multicannons often cannot be set up in the areas of many bosses. Others may have different restrictions; for example, only black equipment may be used to fight the tormented wraith, and Prayer cannot be used during the fights with the final bosses of Recipe for Disaster.
Independent high-level bossesEdit
These are the most powerful bosses that do not share a lair or dungeon with other bosses. These are amongst the most powerful creatures in RuneScape and, with the exception of the Queen Black Dragon, are mostly killed with a team.
|Name||Level||Description||Attack Style||Slayer category|
|Vorago||10,000||Vorago is currently the highest level monster in RuneScape, with a combat level of 10,000. Vorago is noted as the hardest boss in RuneScape, and as so, requires a team of high-level players. Vorago drops the Seismic wand, Seismic singularity and Tectonic energy, which is used to make Tectonic armour with level 91+ Runecrafting - the best power magic armour currently in-game.|| Magic
|Barrows - Rise of the Six||650 x 6||Barrows - Rise of the Six is an upgraded version of the original Barrows minigame. Players fight the six Barrows brothers simultaneously. There are two rooms, three brothers in each room. The brothers are massively enhanced and in terms of difficulty, on par with Vorago. If all brothers are killed, the chest can be looted. Possible loots include level 90 shields and Malevolent energy, which is used to make Malevolent armour with level 91+ smithing - the best power melee armour currently in-game.|| Magic
|Araxxor and Araxxi||2500 and 3000||Araxxor (2500) and is the third highest level monster, tied with the Kalphite King, while its female mate Araxxi (3000) is the second highest. They are found near Port Phasmatys. Players can choose a pathway to trigger different fights. They have a large variety of mechanics. Araxxi drops components of the Noxious weaponry, level 90 two-handed weapons.|| Magic
|Kalphite King||2500||The Kalphite King is the 4th highest level monster to be on Gielinor, tied to Araxxor, with a combat level of 2500. Found in the Exiled Kalphite Hive south-east of the Bandit Camp Lodestone in the desert. It is known for dropping Drygore weaponry, level 90 main- and off-hand melee weapons in three styles: maces, rapiers and longswords.|| Magic
|WildyWyrm||1337||The WildyWyrm may occasionally spawn in place of a regular lava strykewyrm. They can wander across the whole Wilderness and share the same attack mechanics as regular lava strykewyrms. It shares their unique drops, the wyrm heart, wyrm spike and wyrm scalp with their cousins but with a better drop rate.|| Melee
|Queen Black Dragon||900||The Queen Black Dragon is the strongest dragon found on Gielinor, with a combat level of 900. The QBD is a monster which can only be soloed by members, often for its rare Dragon kiteshield drop, Dragonbone Upgrade Kit, and pieces of the Royal crossbow, the strongest 2-handed crossbow in-game. She is fought in four stages; at the end of each the player must activate an artefact. Once the fourth artefact is activated the fight is over and the player may enter the rewards room and open the chest. The Queen Black Dragon cannot be killed per se; the fight ends by putting her back to sleep.|| Melee
|Corporeal Beast||785||The Corporeal Beast is an extremely powerful monster that may be fought after completion of Summer's End. With a combat level of 785, it is not meant to be taken lightly. Although it is extremely dangerous to fight, players often team up to defeat the Corporeal Beast, as it is the only monster that drops sigils for spirit shields.|| Melee
God Wars DungeonEdit
For each warring deity in the God Wars Dungeon, there is a very powerful leader commonly referred to as a 'general'. Each general also has three bodyguards, one of which uses each style of combat: Melee, Magic and Ranged (with the exception of Nex having four bodyguards and they all use Magic). In addition to the 60 Strength or 60 Agility required to enter the God Wars Dungeon, each general's encampment has further requirements to enter.
|Name||Level||Entry Requirement||Description||Attack Style||Slayer category|
|Nex||1001||70 Agility||Nex is the leader of the Zarosian army trapped within the God Wars Dungeon by the forces of Saradomin, Zamorak, Bandos and Armadyl. She has a number of immensely powerful attacks in her arsenal, some of which can hit up to 6848 damage. Rather than following the trend of other God Wars Dungeon bosses and having three bodyguards, Nex is assisted by four mages, each of which represents one of the elements of the Ancient Magicks. Reaching her requires assembling a key to bypass the frozen door, the four pieces of which may be dropped within the monsters of the Saradominist, Zamorakian, Bandosian and Armadylean encampments. Thus, Nex effectively has all of the requirements of the other God Wars Dungeon bosses to reach. Nex drops many unique items: Torva armour, Pernix armour, and Virtus armour, which are three full sets of power armour, and the Virtus wand, Virtus book, and zaryte bow. Her minions and bodyguards drop ancient ceremonial robes.|| Magic
|K'ril Tsutsaroth||650||70 Constitution||K'ril Tsutsaroth is the level 650 demonic general of Zamorak. His melee attacks can poison players although it is not as strong as it was prior to EoC. He can occasionally use a special ability dealing massive damage to his target and draining their prayer points by half. His bodyguards are the demons Tstanon Karlak, Zakl'n Gritch and Balfrug Kreeyath. He drops the Zamorak hilt, and he and his bodyguards also drop the robes of subjugation, Zamorakian spear, and steam battlestaff.|| Magic
|General Graardor||624||70 Strength||General Graardor is one of the last known living ourgs. He is the level 624 general of Bandos and is the most popular God Wars Dungeon general to kill, despite his devastating Melee and Ranged attacks. His bodyguards are Sergeant Strongstack, Sergeant Grimspike and Sergeant Steelwill. General Graardor drops the Bandos hilt and guaranteed ourg bones, and he and his bodyguards drop Bandos armour.|| Melee
|Commander Zilyana||596||70 Agility||Commander Zilyana is the level 596 Icyene general of Saradomin, attacking rapidly and accurately with both Melee and Magic. Her bodyguards are Starlight, Growler and Bree. She drops the Saradomin hilt, and she and her bodyguards drop the Saradomin sword, Armadyl crossbow, and amulets of Saradomin.|| Magic
|Kree'arra||580||70 Ranged||Kree'arra the Aviansie is the level 580 general of Armadyl. Being a guardian and leader of the aviansie, he cannot be attacked with melee weapons, though he uses all three combat styles himself. His bodyguards are Flight Kilisa, Flockleader Geerin and Wingman Skree. Kree'arra himself drops the Armadyl hilt, and he and his bodyguards drop Armadyl armour.|| Magic
Heart of GielinorEdit
Heart of Gielinor, is the sequel of God Wars Dungeon, set in the Sixth Age. Like God Wars Dungeon, it also features four warring factions, each with an unique and powerful boss. The warring factions are the armies of Sliske, Zamorak, Zaros and Seren — the four entities from Freneskae. Similarly to the God Wars Dungeon, each faction requires level 80 in a specific skill. All those bosses drop dormant Anima Core equipment, which can be combined with crests of all Gods to obtain God-specific armor, and level 85 weapons, which provide accuracy and damage in differing tiers.
|Name||Level||Entry Requirement||Description||Attack Style|
|Gregorovic||1000||80 Prayer||Gregorovic is the general of Sliske's army. Once a human, desperately trying to fight death, he eventually sold his soul to Sliske in return for eternal life. Gregorovic uses a combination of Ranged and Melee attacks. His attacks are extremely poisonous, which makes using countermeasures a requirement. He has the ability to summon spirits which will increase the potency of his attacks; during the fight, he will also spawn two weak clones of himself. Gregorovic drops the Crest of Sliske, which can be combined with Anima Core equipment, the Shadow glaive level 85 thrown weaponry, as well as several useful items.|| Ranged
|Twin Furies||1000 x 2||80 Ranged||The Twin Furies — Nymora, the Vengeful and Avaryss, the Unceasing are the Zamorakian generals in the Heart of Gielinor. They are Avernic demons who have been in Zamorakian service since the Gielinorian God Wars. The player simultaneously fights both Nymora and Amaryss, thus needing to expect damage from two sides. The furies, however, share their health pool. Nymora mainly uses Ranged attacks, while Avaryss focuses on Melee. They also use several special attacks involving their environment. They drop Blade of Avaryss and Blade of Nymora, level 85 swords, and the Crest of Zamorak, as well as many general useful items.|| Melee
|Vindicta||1000||80 Attack||Vindicta is the level 1000 Zarosian general in the Heart of Gielinor. She is a Dragon Rider, daughter of Morvannon and Hannibus, who grew up in the Grotworm Lair and is now seeking to avenge the murder of Morvannon. She is accompanied in the fight by her mount, Gorvek. Vindicta's auto-attacks hit very hard, her mount Gorvek will also use dragonfire in the fight. Vindicta drops the Dragon Rider lance, the Crest of Zaros and various general items.|| Melee
|Helwyr||1000||80 Magic||Helwyr is the Seren general in the Heart of Gielinor and a member of the Cywir Clan of the elves. He has taken on the form of a large predator he slaid while on Tarddiad. During the battle, Helwyr only uses Melee attacks, so it is advised to keep a distance. He will also summon mushrooms in his arena, which puff out a stunning and damaging gas, as well as use typeless damage bleeds. Helwyr drops the Wand of the Cywir elders, as well as several the Crest of Seren.||Melee|
Monastery of AscensionEdit
The Legiones are extremely powerful members of the Order of Ascension. They may only be fought with 95 Slayer after their respective Keystone is obtained, which are dropped by other members of the order, and they themselves are capable of dropping them. They can be fought alone or with a Social slayer partner, and they are level 304, each having a special ability that makes them different from the rest, although they are all capable of throwing electricity on the floor, similar to Commander Zilyana in hard mode. They are capable of dropping signets for the Ascension crossbow and the Off-hand Ascension crossbow, level 90 dual-wielded crossbows.
|Legio Primus||Lightning strikes become increasingly powerful.|
|Legio Secundus||Uses lightning strikes more often.|
|Legio Tertius||Summons fellow Ascended to aid him.|
|Legio Quartus||Teleports the player next to or near him.|
|Legio Quintus||Creates the Line of Ascension, which deals heavy damage when walked over or on.|
|Legio Sextus||Uses lightning exclusively, which lasts for seven seconds rather than three.|
Independent Mid/Low-level bossesEdit
|Name||Level||Description||Attack Style||Slayer category|
|Exiled Kalphite Queen||356||The Exiled Kalphite Queen is the ruler of the exiled kalphites, found at the bottom of the Exiled Kalphite Hive in the Kharidian Desert. She is essentially a harder version of the Kalphite Queen, released as a side boss to the Kalphite King.|| Magic
|Kalphite Queen||333||The Kalphite Queen is the ruler of the kalphites; she can be found at the bottom of the Kalphite Hive in the Kharidian Desert. Unlike many other bosses, she has two forms, both of which are level 333, and she uses protection prayers to block different attack styles. Her attacks are extremely accurate and very deadly for players who are unprepared for them. She drops the dragon chainbody and dragon two-handed sword; she also drops her head, which can be mounted in a player-owned house.|| Magic
|Chaos Elemental||305||The Chaos Elemental is a level 305 creature of pure chaos that resides in deep Wilderness, near the Rogue's Castle. In addition to attacking with all three combat styles, it can teleport players around it and unequip their items. It drops the dragon two-handed sword, and various pieces of Ancient Warriors' Equipment.|| Magic
|King Black Dragon||276||The King Black Dragon is an enormous, three-headed dragon who uses various different dragonfire-based attacks which can freeze and poison the player. He also uses a melee attack. He drops various drops, including the Draconic visage, Dragon-rider boots and the Dragon Rider Gauntlets.|| Magic
|Giant Mole||230||The Giant Mole is, true to its name, an enormous mole, level 230, that lives in its lair under Falador Park. During combat the Giant Mole attacks with melee and burrows around its rather large lair, gaining different special abilities in each area. It drops various items, such as Mole claws and Mole skins which can be traded to Wyson for bird's nests. It also drops clingy moles and numbing roots.||Melee||N/A|
|Barrows brothers||150 7x||The seven Barrows brothers can be thought of as bosses, as each is quite powerful and together they are fought during the Barrows minigame. The brothers are all level 150 save for Akrisae, who is level 115. Their combat styles are Ahrim the Blighted (magic), Dharok the Wretched (melee), Guthan the Infested (melee), Karil the Tainted (ranged), Torag the Corrupted (melee), Verac the Defiled (melee) and Akrisae the Doomed (magic). The Ritual of the Mahjarrat is required in order to fight Akrisae. Each is an undead spirit and wears a certain set of equipment that gives a certain set effect; this equipment, known as Barrows equipment, can be obtained from the activity, and is highly popular as the sets are among the most powerful combat equipment in the game.|| Magic
|Tormented Wraith||42||The tormented wraith is the level 60 spirit of a being who was tortured and killed by the Black Knights. It roams the Dark Warriors' Fortress in the Spirit Realm, eternally seeking revenge on the Black Knights who tortured it. Because of its extreme animosity towards the Black Knights, only black weapons may be used to fight it. The tormented wraith is one of the two monsters (the other being the Corporeal Beast) to drop holy elixirs, which are used to create blessed spirit shields.||Magic||Ghosts|
|Dragith Nurn||26||The undead Dragith Nurn can be found in the Lumbridge Catacombs, where he imprisoned himself prior to his death to avoid his undead creations from overrunning Lumbridge. He has risen from his grave due to an enchantment he cast upon himself, however, and his tomb is once again accessible due to the efforts of three Zamorakian cultists. Dragith can only be fought after The Blood Pact. He drops the fifth and final part of the Mask of Dragith Nurn.||Magic|
Three level 303 Dagannoth Kings lair deep under Waterbirth Island. Altogether the Kings drop several unique items, such as Seercull, dragon hatchets, berserker rings and mud battlestaves. They also drop a variety of Fremennik-related arms and armour, such as archer helms and skeletal armour. They all have the Slayer category of Dagannoths.
|Dagannoth Supreme||Dagannoth Supreme is the Ranged Dagannoth King, and therefore is weak to stabbing attacks. It is the only King to drop Spined armour and Archers' rings. Balmung is effective against him.||Ranged|
|Dagannoth Prime||Dagannoth Prime is the Magic Dagannoth King, and therefore is weak to arrows. It is the only King to drop Skeletal armour and Seers' rings.||Magic|
|Dagannoth Rex||Dagannoth Rex is the Melee Dagannoth King, and therefore is weak to fire. It is the only King to drop Rock-shell armour, Warrior rings and Berserker rings.||Melee|
Raids are sequences of boss fights. Currently, the only raid is Liberation of Mazcab.
Liberation of MazcabEdit
|Beastmaster Durzag||2000||Beastmaster Durzag is the first boss of Liberation of Mazcab. Before fighting Durzag himself, the team will face airut, chargers, and his pet beast, Cormes. During the fight, Beastmaster Durzag summons two pets — Krar and Tuz which will deal additional damage, and 15 Chargers, which are initially in cages. Beastmaster Durzag can be looted once every 48 hours for a chance of Primeval, Tempest and Teralith equipment.|| Magic
|Yakamaru||10,000||Yakamaru is the second boss of Liberation of Mazcab. It is fought on a beach in Mazcab with several pools of water and can only be fought after Beastmaster Durzag has been defeated. Every pool has a different mechanic. After one version of Yakamaru is killed, Yakamaru summons four versions of itself. Yakamaru can spawn Jellyfish to its aid. Like Beastmaster Durzag, Yakamaru can be looted once every 48 hours for a chance of Primeval, Tempest and Teralith equipment.|| Magic
Bosses that are fought during a minigame.
|Har-Aken||800||Fight Kiln||Har-Aken is the final boss of the Fight Kiln minigame, having a combat level of 800. It is the strongest of all lava creatures (TzHaar and TokHaar). It uses magic and ranged attacks by using its tentacles. It will pop up its head, which is the only point where it can be killed, every 72 seconds, staying up for only 27 seconds before disappearing again.|| Magic
|TzTok-Jad||702||TzHaar Fight Cave||TzTok-Jad is the final boss of the TzHaar Fight Cave minigame. It is level 702 and is extremely dangerous as all of its attacks, which hit from every side of the combat triangle, can each deal up to 9000+ damage. Additionally, TzTok-Jad summons Yt-HurKot to rapidly heal it once it reaches half health. The reward for defeating TzTok-Jad is 16,064 tokkul and the much-coveted fire cape. Kuradal the Slayer master will sometimes assign the entirety of the TzHaar Fight Cave minigame as a Slayer assignment; under these circumstances, another reward for defeating TzTok-Jad is 25,000 Slayer experience.|| Magic
|Penance King||None||Barbarian Assault||The Penance King is the boss of the hard mode version of Barbarian Assault. Like the Queen, he cannot be damaged by conventional weapons. The team must gather materials to create the only weapons that can - flamethrowers - and read an incantation from their scrolls in the correct order to make him vulnerable to the flamethrowers.||Melee|
|Penance Queen||None||Barbarian Assault||The Penance Queen is the boss of the Barbarian Assault minigame; she is fought during the tenth and final wave. She uses rapid melee and Ranged attacks and can only be damaged with omega eggs fired from the egg launcher. Defeating her earns players 80 honour points in their chosen roles, and 5 points in the other roles.||Melee
|Avatar of Creation and Avatar of Destruction||65||Soul Wars||In the Soul Wars minigame are two colossal avatars, the Avatar of Creation and Avatar of Destruction. Both are level 65. Each avatar is on one team's side, and the ultimate objective of Soul Wars is for each team to defeat its opposing team's avatar. Each avatar has a certain Slayer level required to fight it; the level can be lowered by team members using soul fragments on soul obelisk, or raised by players burying bones on their grave. Chances to raise avatar's level by burying bones is 50%||Melee|
Distraction and Diversion bossesEdit
Those bosses have restrictions on when they can be fought, or how many times they can be fought at any given time.
|Agoroth||None||Agoroth||Agoroth is a large Crassian, who emerges from the Empress after you have defeated four of his tentacles. His attacks include a water jet that knocks you back to the back of the boat where the boss fight is situated, where upon his large tentacles hit you for a large amount of damage and melee attack where he snaps you with his claws. After his health depletes halfway, every other attack from the player will be blocked, and Agoroth will spray acid from above, dealing damage, and the only way to avoid this is to either run away from shaded spots, as acid will land there, or walk up the ladders in the rear of the ship. You can also run up the ladders at the rear of the ship and it will shield you from any of his attacks melee or ranged.|| Twice a week (P2P);|
Once a week (F2P)
|Cliff||Scaled||Troll Invasion||Cliff is a mighty troll encountered during the final wave of the Troll Invasion Distraction and Diversion. He attacks with all three combat styles, hits very hard, and can teleport players around. He may be fought once a month for an experience reward, or unlimited times for fun.||Once a month|| Magic
|Demon boss||200||Demon Flash Mobs||Demon bosses are encountered as part of the Demon Flash Mobs Distraction and Diversion. They serve as the main boss of the activity, although only one appears within each mob. It is protected by six imp heralds, four lesser demons and two black demons; the latter two it will devour to recover lost health. Its name and, to some degree, its appearance is random, but the prefix and suffix of its name will affect its abilities. It is killed for Demonic title scrolls and Demon slayer equipment.||Appears in random locations|| Magic
|Bork||107||Bork||Bork is a level 107 ork who resides in the Chaos Tunnels, and is loyal to the Dagon'hai faction of Zamorakians. Bork is fought at the conclusion of the miniquest Chaos Tunnels: The Hunt for Surok, and can be killed once per day thereafter. He gives 5,000 Slayer experience the first time he is killed, and 1500, 3000, 4000, or 8000 experience every time he is defeated afterwards. In addition to his powerful melee attacks, Bork can summon several Ork legions to assist him, which use melee and Ranged. Additionally, Surok Magis (or an anonymous but functionally equivalent Dagon'hai Elite mage after the miniquest) will attack any players who challenge Bork with very powerful Magic attacks. Bork is can be slain daily for his Slayer experience and his guaranteed drop of various charms and gems.||Once per day||Melee|
|Skeletal Horror||91, 86, 84, 81||Skeletal Horror||The skeletal horror is a level 91 amalgamation of bones gathered from various monsters across RuneScape at the behest of the Odd Old Man. It may be fought once per week, giving 10,000 Slayer experience and 7,000 Prayer experience the first time it is defeated, and up to 12,500 Slayer experience and 10,000 Prayer experience each time thereafter. The skeletal horror uses melee and Magic attacks, and as the battle progresses, its limbs fall off. Its two drops can be an clue scroll (elite) and a Crystal triskelion fragment.||Once a week|| Magic
|The Phoenix||84||Phoenix Lair||The Phoenix is a level 84 avian of fire that may be fought, once per day, after completion of the In Pyre Need quest. She uses powerful Magic attacks in combat, and once defeated, she must be set aflame on the pyre in her lair; she will rise from the ashes as a hatchling, and will have fully regrown by the next day. The first time she is defeated, she gives 5,000 Slayer experience, 7,500 Firemaking experience, and 3,000 Fletching experience; for each kill thereafter the Slayer experience is reduced to 500, but the other experience rewards do not change. Additionally, she will reward players with 5 phoenix quills each time she is defeated.||Once per day||Magic|
|Champion's Challenge bosses||Varies||Champion's Challenge||The Champion's Challenge Distraction and Diversion features killing champions of 12 different races, who have been summoned to the Champions' Guild using Champions' scrolls. They vary in size and combat level.||Must have a Champions' scroll||Varies|
A large number of quests involve and/or conclude with a battle against a powerful monster, which often is or is related to the quest's main antagonist. Except where otherwise noted, these bosses cannot be fought once their respective quests have been completed. However, many of them could be fought after in the Dominion Tower, after some other requirements have been met.
A sub-boss is a powerful or semi-powerful monster fought as a prelude to the actual boss fight.
- The Abomination is the mutated form of Tarshak the dragonkin and is battled during Hero's Welcome.
- Agoroth is the leader of the Crassians and is fought in A Shadow over Ashdale. After the quest, he may be fought twice a week for Black pearls or coins.
- Agrith Naar, a demon summoned to Gielinor by a group of Zamorakians, is fought at the end of Shadow of the Storm.
- The Arzinian Avatar is the boss of Between a Rock....
- Arrg is the strongest mountain troll in the game, and is the boss monster of Troll Romance.
- The Balance Elemental is a Guthixian avatar that guards the Stone of Jas. It is one of the final boss monsters of the Grandmaster quest While Guthix Sleeps.
- The Bandos Avatar is the final boss of The Chosen Commander. He is the Goblin High Priest under the control of the god Bandos.
- The Banshee Mistress is the boss of Smoking Kills.
- Barrelchest, a hulking artificial construct controlled by Mi-Gor, is the boss of The Great Brain Robbery.
- A Black Demon controlled by Glough is the final challenge in The Grand Tree.
- The Black Knight Titan is the scourge of the Fisher Realm and is fought during Holy Grail.
- Bouncer is a powerful hellhound, the pet of General Khazard, and is fought during Fight Arena.
- The Cave Wolf Matriarch is fought during Carnillean Rising.
- Char is a powerful Auspah fought at the end of the Master quest, The Firemaker's Curse
- Chronozon is a demon who is the boss of Family Crest.
- Count Draynor is a notorious vampyre who is the boss of Vampyre Slayer. He is one of the few free-to-play bosses.
- The Culinaromancer is a powerful sorcerer who draws his power from food. He is the main antagonist of the Recipe for Disaster quest series, and is the final boss of its conclusion, Defeating the Culinaromancer.
- Dad is a mountain troll who is fought during Troll Stronghold.
- There are a few Dagannoth bosses:
- The Dark Lord is fought during Plague's End. It is a fragment of Seren's mind that was imprisoned inside the Temple of Light but with its voice drove any inside the Underground Pass mad.
- Lensig, under the alias "Dawn", is a witch who is fought during The Death of Chivalry.
- The decaying avatar, a failing Soul Wars avatar, is the sub-boss of the Grandmaster quest Nomad's Requiem.
- Delrith is an ancient demon who was summoned to destroy Varrock; he is the boss of Demon Slayer. He is one of the few free-to-play bosses.
- The Dramen Tree Spirit guards the dramen tree within Entrana Dungeon, and is the boss of Lost City. Because of the restrictions on Entrana, no weapons or armour may be used to fight the tree spirit.
- Draugen is a spirit fought as part of The Fremennik Trials.
- Elvarg is a green dragon who has decimated the island of Crandor, where she roosts. She is the final boss of Dragon Slayer, and is one of the few free-to-play bosses.
- An Evil Spirit is the boss monster of Rum Deal.
- The Fairy Godfather, along with his army of orks, is the final boss of Fairy Tale III - Orks Rift.
- The Foreshadow is a shadow version of the player created by Sliske, fought during Dishonour among Thieves.
- Ikadia the Exile, the elder leader of the chaos druids, the sub-boss of Birthright of the Dwarves.
- Hreidmar is one of the final and strongest bosses of Birthright of the Dwarves.
- Colonel Grimsson is the Butcher of Barendir, is the boss of King of the Dwarves. And is one of the final and strongest bosses of Birthright of the Dwarves.
- Gadderanks is a human supporter of the vampyric regime in Morytania. He is fought during In Aid of the Myreque.
- General Khazard can be optionally fought during Fight Arena.
- The Giant Roc is a large avian fought atop Trollheim during My Arm's Big Adventure. He has the uncommon ability to knock players around the area with his massive wings.
- A giant scarab is fought at the end of Contact!. Another, weaker scarab is fought close to the end of Dealing with Scabaras.
- The Giant Sea Snake is the boss of Royal Trouble.
- Glod is an enormous giant who resides in the cloud world above the magic beanstalk that players plant during Grim Tales; he is the quest's boss. He can disable prayers and force players towards or away from him.
- The ice demon prowls the halls of the fortress at Ghorrock and is the boss of The Temple at Senntisten.
- The Ice Troll King, leader of the ice trolls, is the boss of The Fremennik Isles.
- The Jungle demon is a powerful demon who serves as the final boss of Monkey Madness.
- A Khazard Ogre is one of the bosses of Fight Arena.
- Koschei the Deathless is a Fremennik warrior who cannot be truly killed. He must be defeated in battle three times in a row as part of The Fremennik Trials.
- Lowerniel Drakan is the tyranical dictator of Morytania, he is fought in the final battle during The Lord of Vampyrium.
- While Lucien is present at the final battle during The Ritual of the Mahjarrat, players do not directly defeat him. Rather, he summons two enhanced ice titans and two ice demons that players battle.
- Me, who takes the form of players who fight him or her, is fought at the end of Lunar Diplomacy.
- Melzar the Mad is the keeper of Melzar's Maze. He is a sub-boss of Dragon Slayer.
- A powerful Moss giant must be fought, without weapons, armour, or Prayer, to obtain the Consecration seed in Roving Elves.
- Nezikchened is a black demon who is fought three times during Legends' Quest, including at the quest's climax.
- Nial Swiftfling is a Fremennik warrior who was cursed and turned into a yeti. He is fought during Glorious Memories.
- Nomad, the mysterious warden of the Soul Wars activity, is also the final boss of the Grandmaster quest Nomad's Requiem, as well as the Master quest Nomad's Elegy. He is extremely powerful and is widely regarded as one of the most difficult quest bosses to defeat in the game.
- The Pest Queen is the mother of all pests, the scourges of the Void Knights. She is the final boss of the Grandmaster quest The Void Stares Back.
- The Possessed Priest is the boss of Icthlarin's Little Helper.
- The Sea Troll Queen, ruler of the sea trolls, is the final boss of Swan Song.
- Sigmund is a supporter of H.A.M. who is fought in three quests: Death to the Dorgeshuun, Another Slice of H.A.M., and The Chosen Commander.
- Sir Leye is a Temple Knight who cannot be defeated by any man alive. Thusly, he must be fought as a woman during Recruitment Drive.
- Sir Mordred is the leader of the Renegade Knights and is fought during Merlin's Crystal.
- Slagilith is an animated golem of rock who is fought during One Small Favour. It can be fought after the quest is complete.
- Slash Bash is a strong zogre who is the boss of Zogre Flesh Eaters.
- The Spirit Beast is the terror of the Spirit Realm. It cannot be fought by conventional means, but nonetheless serves as the bosses for Spirit of Summer and Summer's End. During Summer's End, the Spirit Beast has a combat level of 615; it is technically the strongest quest monster in the game.
- Tarn Razorlor is a necromancer and is the boss of the miniquest The Lair of Tarn Razorlor.
- Tolna is a young boy who succumbed to the evils of what later became known as the Dungeon of Tolna. He is the boss of A Soul's Bane, taking the form of a three-headed monster.
- Treus Dayth, now a ghost, was a follower of Drakan who was sealed within the Abandoned Mine. He is the boss of Haunted Mine.
- Ulfric is an undead Fremennik who is the boss of Olaf's Quest.
- Vanstrom Klause, an elite vampyre, is the boss of The Branches of Darkmeyer.
Quests with multiple bossesEdit
Some quests have several boss monsters that must be defeated, usually one after the other.
- The World Wakes
- Do No Evil features three powerful bosses: Leeuni, Ayuni and Eruni. Each uses different combat styles and have unique powers.
- Spirits of the Elid has three bosses: The black golem, grey golem and white golem.
- Desert Treasure has four Zamorakian warriors as bosses: Dessous, Kamil, Fareed and Damis.
- During Land of the Goblins, five undead goblin priests must be defeated: Snothead, Snailfeet, Mosschin, Redeyes and Strongbones.
- The Recipe for Disaster quest series culminates in the final subquest, Defeating the Culinaromancer. Six bosses must be defeated: Agrith Na-Na, Flambeed, Karamel, Dessourt, Gelatinnoth Mother and the Culinaromancer himself. Each of these bosses except for the Culinaromancer is a play on another boss of one of the quests required to finish Recipe for Disaster.
- During Dream Mentor, four boss monsters are fought, in order: The Inadequacy, The Everlasting, The Untouchable and The Illusive.
- There is a miniquest, titled the Desert Slayer Dungeon miniquest, that is available after completing Smoking Kills. Four boss versions of Slayer monsters are fought: The monstrous cave crawler, the basilisk boss, the mightiest turoth and the kurask overlord.
- During Ritual of the Mahjarrat, General Khazard must be first defeated, and then the player battles two Enhanced ice titans together and then two ice demons at once.
- During The Elder Kiln, a very large number of monsters must be defeated, though not all at once: two TzHaar-Ket (Hardened), two TzHaar-Xil (Hardened), TzHaar-Ket-Yit'tal, twelve lava monsters, three TokTz-Ket-Dill, two Ket-Zek, Yt-MejKot, TokHaar-Hur, TokHaar-Xil, TokHaar-Ket, TokHaar-Mej and the TokHaar-Ket Champion.
On 1 November 2011, Jagex released the Dominion Tower, a minigame that allows players to fight bosses from quests they have completed. Players can fight up to 60 unique boss monsters from previous quests, including Nomad, the Pest Queen, Zenevivia, the Balance Elemental, and many others.
At the end of each floor of Daemonheim is a powerful boss monster that must be defeated in order to complete the dungeon. The levels and strengths of these bosses vary according to a combination of factors, including the dungeon's size and complexity rating, but otherwise they will always have the same qualities. Kal'Ger the Warmonger is the strongest in Daemonheim.