Bob may refer to one of these separate beings:
- Bob (cat), the enigmatic black cat
- Evil Bob, the evil doppelgänger of Bob the Jagex Cat. He whisks players away to ScapeRune during the Prison Pete and Evil Bob's Island random events
- Bob (smith), the hatchet seller in Lumbridge
- Bob Sinclair, one of the Sinclair siblings
- Bob Barter, the Herblore Market Price Guide in the Grand Exchange
- A Beast of Burden (often abbreviated to BoB), a type of Summoning familiar
- Bob, another guard of Falador, a Falador guardsman seen during the Garden of Tranquility quest
- Bob, a member of the Flash Mob seen during the Enlightened Journey quest
- Builder Bob, involved in the Lumbridge Rebuildathon
- Guthix's Book of Balance, a god book, commonly referred to as "BoB"
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