It is important to not underestimate Ayuni, as her low combat level is deceiving. Ayuni's main strength is in her melee attack, which is strong and hits very fast and accurately. Like her sisters, Leeuni and Eruni, she is impervious to the effects of poison. She also moves very slowly, at half the speed of walking, which further encourages defeating this opponent with Ranged or Magic. Ayuni is capable of draining the player's Prayer by up to 250 points per attack using her magic and melee attacks, however this is greatly reduced in the Dominion Tower. Using hit and run methods while ranging Ayuni makes this fight easy even without prayer.
When Ayuni's health drops lower, she begins to use teleports to momentarily catch up with you.