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This article is about the 4 dose potion; for the potion flask version, see Antipoison flask.
For the barbarian mix, see Antipoison mix.
This article is about the the standard variant; for the variant encountered while Dungeoneering, see Antipoison (Daemonheim).
Classic Runestone
Antipoison (4) Antipoison (3) Antipoison (2) Antipoison (1)
Release date 27 February 2002 (Update)
Members? Yes
Quest item? No
Tradeable? Yes
Equipable? No
Stackable? No
High Alch 172 coins
Low Alch 115 coins
Destroy Drop
Store price 288 coins
Exchange price 4 dose:
272 coins
3 dose:
103 coins
2 dose:
109 coins
1 dose:
52 coins
Examine X doses of antipoison potion.
Weight 0 kg
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Antipoison detail

An Antipoison is a potion made via the Herblore skill. An antipoison cures poison and reduces poison damage by 100% for 86 seconds.

The number in brackets after the item name indicates the number of doses remaining in the vial and range from 1 to 4.

Members can make one with three doses by using clean marrentill on a vial of water and then adding Unicorn horn dust. This requires level 13 herblore and gives 50 herblore experience.

If the player adds roe to a 2-dose potion, it will become a 2 dose antipoison mix which heals 30 life points.

Antipoisons can be purchased at Jiminua's Jungle Store on Karamja and The Spice is Right in Sophanem.

It is recommended that players use Antipoison++ instead of this potion, as Antipoison++ is cheaper while offering an immunity period eight times longer (12 minutes per dose).


Antipoison (3) Antipoison (3)
Herblore-icon Make-X store icon Make-X GE icon Make-X alchemy icon -
37.5 xp 86 103 172 -
Herblore Herblore level 13
P2P icon Members only? Yes
Item Quantity Price Total
Marrentill potion (unf) Marrentill potion (unf) 1 258 258
Unicorn horn dust Unicorn horn dust 1 2,426 2,426
Total price 2,684

Production costsEdit

This table is based on the Grand Exchange prices of a vial of water, the marrentill, and Unicorn horn dust. It is accurate assuming all three items are bought from the Grand Exchange and the Antipoison is sold afterwards.

Herb state Material cost Profit/loss Profit/xp
Clean 2,562-2,459-49.18
Grimy 2,570-2,467-45.86

Grimy marrentillClean marrentill + Vial of water = Marrentill potion (unf)

Grimy marrentill is cleaned to become Clean marrentill added with a Vial of water to make Marrentill potion (unf).

Marrentill potion (unf) + Unicorn horn dust = Antipoison (3)

Then add Unicorn horn dust to make a 3-dose Antipoison.

Dropping monsters Edit

Monster Combat level Quantity Rarity
Chaos Elemental 305 1 2; Common
Aviansie 69; 71; 73; 79; 83; 84; 89; 92; 94; 97; 131; 137; 148 5 3; Uncommon
Spiritual mage 120; 123 5 3; Uncommon
Druid 33 1 4; Rare
Druidess 33 1 4; Rare
Tribesman 32 1 4; Rare
Skeleton 13; 21; 142 1 5; Very rare

Flask Edit

This potion can be made into an Antipoison flask by using at least six doses of it with a Potion flask. Players do not need a specific level to turn potions into flasks.


  • The idea of a Unicorn Horn in antipoison comes from a popular belief in the Middle Ages that a unicorn's horn could be used to neutralise the effects of poison, and that even possessing one could prolong someone's life.
  • When mixing the antipoison it says unicorn horn instead of unicorn horn dust.
  • If you are poisoned and you have any of the antipoisons in your inventory you can right click your health indicator on your action bar to heal, rather than going to your inventory. This is especially useful when you need to cure poison while having the spellbook, prayer list, or other interface open.

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