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This article is about the 4-dose potion. For the potion flask version, see Antipoison flask.
For the barbarian mix, see Antipoison mix.
This article is about the the standard variant. For the variant encountered while Dungeoneering, see Antipoison (Daemonheim).
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Antipoison detail

An Antipoison is a potion made via the Herblore skill. An antipoison cures poison and reduces poison damage by 100% for 86 seconds.

The number in brackets after the item name indicates the number of doses remaining in the vial and range from 1 to 4.

Members can make one with three doses by using clean marrentill on a vial of water and then adding unicorn horn dust. This requires level 13 herblore and gives 50 herblore experience.

If the player adds roe to a 2-dose potion, it will become a 2 dose antipoison mix which heals 300 life points.

Antipoisons can be purchased at Jiminua's Jungle Store on Karamja and The Spice is Right in Sophanem.

It is recommended that players use antipoison++ instead of this potion, as Antipoison++ is cheaper while offering an immunity period eight times longer (12 minutes per dose).

Price per DoseEdit

Item Price per dose
Antipoison (1) Antipoison (1) 37
Antipoison (2) Antipoison (2) 36
Antipoison (3) Antipoison (3) 30
Antipoison (4) Antipoison (4) 64


Antipoison (3) Antipoison (3)
Herblore-icon-Make-X GE icon
37.5 XP-89
Herblore-icon Herblore level13
P2P icon Members only?Yes
Marrentill potion (unf) Marrentill potion (unf)1387387
Unicorn horn dust Unicorn horn dust1305305
Total price692

Production costsEdit

Herb state Material cost Profit/loss Profit/xp
Clean 504-415-8.3
Grimy 521-432-8.03

Grimy marrentillClean marrentill + Vial of water = Marrentill potion (unf)

Grimy marrentill is cleaned to become clean marrentill added with a vial of water to make marrentill potion (unf).

Marrentill potion (unf) + Unicorn horn dust = Antipoison (3)

Then add unicorn horn dust to make a 3-dose Antipoison.

Dropping monstersEdit

Monster Combat level Quantity Rarity
Chaos Elemental3051Common
Aviansie89; 92; 955Uncommon
Spiritual mage985Uncommon
Tribesman60; 901Rare
Skeleton15; 16; 32; 43; 46; 47; 49; 51; 53; 54; 58; 701Very rare


This potion can be made into an Antipoison flask by using at least six doses of it with a Potion flask. Players do not need a specific level to turn potions into flasks.


  • The idea of a Unicorn Horn in antipoison comes from a popular belief in the Middle Ages that a unicorn's horn could be used to neutralise the effects of poison, and that even possessing one could prolong someone's life.
  • When mixing the antipoison it says unicorn horn instead of unicorn horn dust.
  • If you are poisoned and you have any of the antipoisons in your inventory you can right click your health indicator on your action bar to heal, rather than going to your inventory. This is especially useful when you need to cure poison while having the spellbook, prayer list, or other interface open.

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